2022/06/29 by Mojmír Mutný, Mutný, Mojmír, Tadeusz J. Janik +3 · 3 citations
Biochemistry, Genetics and Molecular Biology · Computer Science · #FOS: Computer and information sciences #Gene Regulatory Network Analysis #Machine Learning (cs.LG) #Machine Learning (stat.ML) #Machine Learning and Algorithms #Methodology (stat.ME) #Reinforcement Learning in Robotics
paper · pdf · doi:10.48550/arxiv.2206.14332
openalex publication_date 2022/06/29 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28
A key challenge in science and engineering is to design experiments to learn about some unknown quantity of interest. Classical experimental design optimally allocates the experimental budget to maximize a notion of utility (e.g., reduction in uncertainty about the unknown quantity). We consider a rich setting, where the experiments are associated with states in a \em Markov chain, and we can only choose them by selecting a \em policy controlling the state transitions. This problem captures important applications, from exploration in reinforcement learning to spatial monitoring tasks. We propose an algorithm -- markov-design -- that efficiently selects policies whose measurement allocation provably converges to the optimal one. The algorithm is sequential in nature, adapting its choice of policies (experiments) informed by past measurements. In addition to our theoretical analysis, we showcase our framework on applications in ecological surveillance and pharmacology.