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Uncertainty Propagation for Echocardiography Clinical Metric Estimation via Contour Sampling

2025/02/18 by Thierry Judge, Judge, Thierry, Olivier Bernard +11
Decision Sciences · Engineering · Medicine · #Advanced Statistical Process Monitoring #Computer Vision and Pattern Recognition (cs.CV) #FOS: Computer and information sciences #Flow Measurement and Analysis #Hemodynamic Monitoring and Therapy

paper · pdf · doi:10.48550/arxiv.2502.12713

openalex publication_date 2025/02/18 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28

Abstract

Echocardiography plays a fundamental role in the extraction of important clinical parameters (e.g. left ventricular volume and ejection fraction) required to determine the presence and severity of heart-related conditions. When deploying automated techniques for computing these parameters, uncertainty estimation is crucial for assessing their utility. Since clinical parameters are usually derived from segmentation maps, there is no clear path for converting pixel-wise uncertainty values into uncertainty estimates in the downstream clinical metric calculation. In this work, we propose a novel uncertainty estimation method based on contouring rather than segmentation. Our method explicitly predicts contour location uncertainty from which contour samples can be drawn. Finally, the sampled contours can be used to propagate uncertainty to clinical metrics. Our proposed method not only provides accurate uncertainty estimations for the task of contouring but also for the downstream clinical metrics on two cardiac ultrasound datasets. Code is available at: https://github.com/ThierryJudge/contouring-uncertainty.

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