2025/05/09 by Yinzhe Wu, Rui, Hongyu, Wu, Yinzhe +11
Computer Science · #Advanced Image Processing Techniques #Computer Vision and Pattern Recognition (cs.CV) #Domain Adaptation and Few-Shot Learning #FOS: Computer and information sciences #Generative Adversarial Networks and Image Synthesis
paper · pdf · doi:10.48550/arxiv.2505.05855
openalex publication_date 2025/05/09 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/02
Multi-contrast super-resolution (MCSR) is crucial for enhancing MRI but current deep learning methods are limited. They typically require large, paired low- and high-resolution (LR/HR) training datasets, which are scarce, and are trained for fixed upsampling scales. While recent self-supervised methods remove the paired data requirement, they fail to leverage valuable population-level priors. In this work, we propose a novel, decoupled MCSR framework that resolves both limitations. We reformulate MCSR into two stages: (1) an unpaired cross-modal synthesis (uCMS) module, trained once on unpaired population data to learn a robust anatomical prior; and (2) a lightweight, patient-specific implicit re-representation (IrR) module. This IrR module is optimized in a self-supervised manner to fuse the population prior with the subject's own LR target data. This design uniquely fuses population-level knowledge with patient-specific fidelity without requiring any paired LR/HR or paired cross-modal training data. By building the IrR module on an implicit neural representation, our framework is also inherently scale-agnostic. Our method demonstrates superior quantitative performance on different datasets, with exceptional robustness at extreme scales (16x, 32x), a regime where competing methods fail. Our work presents a data-efficient, flexible, and computationally lightweight paradigm for MCSR, enabling high-fidelity, arbitrary-scale