2012/04/25 by Paul T. Edlefsen, Edlefsen, Paul T., Arthur P. Dempster +1
Computer Science · Mathematics · Medicine · #Applications (stat.AP) #Bayesian Methods and Mixture Models #FOS: Computer and information sciences #Hepatitis C virus research #Methodology (stat.ME) #Statistical Methods and Inference #stat.AP #stat.ME
paper · pdf · doi:10.48550/arxiv.1204.5724
This is an incomplete draft (missing refs, results)
arxiv created 2012/04/25 · openalex publication_date 2012/04/25 · arxiv updated 2012/04/26 · openalex created_date 2016/06/24 · openalex updated_date 2026/07/28
We introduce an extension of nonparametric DS inference for arbitrary univariate CDFs to the case in which some failure times are (right)-censored, and then apply this to the problem of assessing evidence regarding assertions about relative risks across two populations. The approach enables exploration of the sensitivity of survival analyses to assumed independence of the missing data process and the failure proces. We present an application to the partially efficacious RV144 (HIV-1) vaccine trial, and show that the strength of conclusions of vaccine efficacy depend on assumptions about the maximum failure rates of the subjects lost-to-followup.