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Modified disease activity scores that include twenty-eight-joint counts development and validation in a prospective longitudinal study of patients with rheumatoid arthritis

1995/01/01 by M. L. L. Prevoo, M.L.L. Prevoo, Martin A. van't Hof +8 · 6,254 citations
Medicine · #Alternative medicine #Arthritis #Clinical psychology #Construct validity #Disease #Internal medicine #Joint disease #Medicine #Osteoarthritis #Osteoarthritis Treatment and Mechanisms #Pathology #Physical therapy #Psychometrics #Rheumatoid Arthritis Research and Therapies #Rheumatoid arthritis #Spondyloarthritis Studies and Treatments

paper · open access · doi:10.1002/art.1780380107

published in Arthritis & Rheumatism 38(1), 44-48 (Wiley)

openalex publication_date 1995/01/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/01

Abstract

OBJECTIVE: The development and validation of Modified Disease Activity Scores (DAS) that include different 28-joint counts. METHODS: These scores were developed by canonical discriminant analyses and validated for criterion, correlational, and construct validity. The influence of disease duration on the composition of the DAS was also investigated. RESULTS: No influence of disease duration was found. The Modified DAS that included 28-joint counts were able to discriminate between high and low disease activity (as indicated by clinical decisions of rheumatologists). CONCLUSION: The Modified DAS are as valid as disease activity scores that include more comprehensive joint counts.

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