Biochemical Coupling Through Emergent Conservation Laws

2018/06/28 by John C. Baez, Blake S. Pollard, Baez, John C. +5
Biochemistry, Genetics and Molecular Biology · #Chemical Physics (physics.chem-ph) #FOS: Biological sciences #FOS: Physical sciences #Microbial Metabolic Engineering and Bioproduction #Molecular Networks (q-bio.MN)

paper · pdf · doi:10.48550/arxiv.1806.10764

openalex publication_date 2018/06/28 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28

Abstract

Bazhin has analyzed ATP coupling in terms of quasiequilibrium states where fast reactions have reached an approximate steady state while slow reactions have not yet reached equilibrium. After an expository introduction to the relevant aspects of reaction network theory, we review his work and explain the role of emergent conserved quantities in coupling. These are quantities, left unchanged by fast reactions, whose conservation forces exergonic processes such as ATP hydrolysis to drive desired endergonic processes.

Citations

• General mass action kinetics

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