Diagnosis of Alzheimer's Disease
1985/11/01 by Z. S. Khachaturian, Zaven S. Khachaturian · 46 citations
Medicine · #Dementia and Cognitive Impairment Research #Alzheimer's disease research and treatments #Frailty in Older Adults
paper · doi:10.1001/archneur.1985.04060100083029
Abstract
Early and accurate diagnosis of Alzheimer's disease (AD) has a major impact on the progress of research on dementia. To address the problems involved in diagnosing AD in its earliest stages, the National Institute on Aging, the American Association of Retired Persons, the National Institute of Neurological and Communicative Disorders and Stroke, and the National Institute of Mental Health jointly sponsored a workshop for planning research. The purpose of the meeting was to identify the most important scientific research opportunities and the crucial clinical and technical issues that influence the progress of research on the diagnosis of AD. The 37 participants included some of the most knowledgeable and eminent scientists and physicians actively involved in the study of AD. The participants were divided among six panels representing the disciplines of neurochemistry, neuropathology, neuroradiology, neurology, neuropsychology, and psychiatry. Within each of the panels, participants discussed specific areas of research requiring further
Cited by
- A Clinicopathologic Study of 100 Cases of Parkinson's Disease
- Neuronal Loss Is Greater in the Locus Coeruleus Than Nucleus Basalis and Substantia Nigra in Alzheimer and Parkinson Diseases
- Cerebral Infarction in Alzheimer's Disease Is Associated With Severe Amyloid Angiopathy and Hypertension
- The Natural History of Alzheimer's Disease
- Regional Distribution of Neurofibrillary Tangles and Senile Plaques in the Cerebral Cortex of Very Old Patients
- A novel membrane protein, encoded by the gene covering KIAA0233, is transcriptionally induced in senile plaque-associated astrocytes
- Aging and Alzheimer's Disease: Lessons From the Nun Study
- Predictors of Decline in Alzheimer's Disease
- Accuracy of the Clinical Diagnosis of Alzheimer Disease at National Institute on Aging Alzheimer Disease Centers, 2005–2010
- Neuropathology of Cognitively Normal Elderly
- Oxidative Damage Is the Earliest Event in Alzheimer Disease
- Quantitative 1H and 31P MRS of PCA extracts of postmortem Alzheimer's disease brain
- Butyrylcholinesterase reactivity differentiates the amyloid plaques of aging from those of dementia
- Association of PPP2R1A with Alzheimer's disease and specific cognitive domains
- Molecular, Structural, and Functional Characterization of Alzheimer's Disease: Evidence for a Relationship between Default Activity, Amyloid, and Memory
- Stable and predictive functional domain selection with application to brain images
- Structural imaging of hippocampal subfields in healthy aging and Alzheimer’s disease
- Sex differences for regional pathology in people with a high likelihood of Lewy body dementia phenotype based on underlying pathology
- An english translation of alzheimer's 1907 paper, “über eine eigenartige erkankung der hirnrinde”
- Controversial Past, Splendid Present, Unpredictable Future: A Brief Review of Alzheimer Disease History
- Effects of rs3846662 Variants on HMGCR mRNA and Protein Levels and on Markers of Alzheimer’s Disease Pathology
- RNA oxidation is a prominent feature of vulnerable neurons in Alzheimer's disease. [europepmc]
- Mitochondrial abnormalities in Alzheimer's disease. [europepmc]
- Molecular, structural, and functional characterization of Alzheimer's disease: evidence for a relationship between default activity, amyloid, and memory. [europepmc]
- Alzheimer disease with amygdala Lewy bodies: a distinct form of alpha-synucleinopathy. [europepmc]
- Staging of neurofibrillary pathology in Alzheimer's disease: a study of the BrainNet Europe Consortium. [europepmc]
- Consortium to Establish a Registry for Alzheimer's Disease (CERAD): the first twenty years. [europepmc]
- Neuropathology and cognitive impairment in Alzheimer disease: a complex but coherent relationship. [europepmc]
- Neuropathology of nondemented aging: presumptive evidence for preclinical Alzheimer disease. [europepmc]
- Multimodal techniques for diagnosis and prognosis of Alzheimer's disease. [europepmc]
- Alzheimer's disease: synaptic dysfunction and Abeta. [europepmc]
- Alzheimer disease. [europepmc]
- Introduction to the recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. [europepmc]
- Neuropathologically defined subtypes of Alzheimer's disease with distinct clinical characteristics: a retrospective study. [europepmc]
- Impaired mitochondrial biogenesis contributes to mitochondrial dysfunction in Alzheimer's disease. [europepmc]
- Accuracy of the clinical diagnosis of Alzheimer disease at National Institute on Aging Alzheimer Disease Centers, 2005-2010. [europepmc]
- Overview and findings from the religious orders study. [europepmc]
- Overview and findings from the rush Memory and Aging Project. [europepmc]
- Preclinical Alzheimer's disease: Definition, natural history, and diagnostic criteria. [europepmc]
- Cholinesterase inhibitors as Alzheimer's therapeutics (Review). [europepmc]
- The neuropathological diagnosis of Alzheimer's disease. [europepmc]
- An atlas of cortical circular RNA expression in Alzheimer disease brains demonstrates clinical and pathological associations. [europepmc]
- Visualization of neurofibrillary tangle maturity in Alzheimer's disease: A clinicopathologic perspective for biomarker research. [europepmc]
- Genomic atlas of the proteome from brain, CSF and plasma prioritizes proteins implicated in neurological disorders. [europepmc]
- Profound loss of layer II entorhinal cortex neurons occurs in very mild Alzheimer's disease. [europepmc]
- Matrix metalloproteinase-9 (MMP-9) is synthesized in neurons of the human hippocampus and is capable of degrading the amyloid-beta peptide (1-40). [europepmc]
Related