Lobar Distribution of Cerebral Microbleeds

2011/05/01 by Dymph J. Mesker, Mariëlle M.F. Poels, Mariëlle M. F. Poels +7 · 22 citations
Medicine · Neuroscience · #Intracerebral and Subarachnoid Hemorrhage Research #Cerebrospinal fluid and hydrocephalus #Acute Ischemic Stroke Management

paper · pdf · doi:10.1001/archneurol.2011.93

Abstract

OBJECTIVE: To investigate the distribution of lobar microbleeds over the different lobes, taking into account lobar volume and clustering effects of multiple microbleeds. DESIGN: Population-based, cross-sectional analysis. SETTING: The Rotterdam Scan Study. PARTICIPANTS: A total of 198 persons (age range, 61-95 years) with lobar microbleeds. MAIN OUTCOME MEASURES: Distribution of microbleeds over different lobes. RESULTS: We found that lobar cerebral microbleeds occurred significantly more often in the temporal lobe, a region known to be more affected in cerebral amyloid angiopathy. CONCLUSION: This study corroborates the presumed association of lobar microbleeds with cerebral amyloid angiopathy.

Citations

• Microbleed Topography, Leukoaraiosis, and Cognition in Probable Alzheimer Disease From the Sunnybrook Dementia Study

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• Estimating Total Cerebral Microinfarct Burden From Diffusion-Weighted Imaging. [europepmc]
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• Diagnostic Significance of Cortical Superficial Siderosis for Alzheimer Disease in Patients with Cognitive Impairment. [europepmc]
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• Ontario Neurodegenerative Disease Research Initiative (ONDRI): Structural MRI Methods and Outcome Measures. [europepmc]
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• Current Management and Therapeutic Strategies for Cerebral Amyloid Angiopathy. [europepmc]
• Association between antiplatelet medication and cerebral microbleeds in stroke-free population. [europepmc]
• White matter degradation near cerebral microbleeds is associated with cognitive change after mild traumatic brain injury. [europepmc]
• Neuropathologic correlates of cerebral microbleeds in community-based older adults. [europepmc]
• Preventing spontaneous cerebral microhemorrhages in aging mice: a novel approach targeting cellular senescence with ABT263/navitoclax. [europepmc]
• Longitudinal detection of gait alterations associated with hypertension-induced cerebral microhemorrhages in mice: predictive role of stride length and stride time asymmetry and increased gait entropy. [europepmc]
• Neuroradiological Findings in Cerebral Amyloid Angiopathy with a Particular Consideration of the Boston Criteria 2.0: An Imaging Review. [europepmc]
• Susceptibility-Weighted Imaging (SWI): Technical Aspects and Applications in Brain MRI for Neurodegenerative Disorders. [europepmc]

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