Permanent Pacemaker and Implantable Cardioverter Defibrillator Infection
2007/04/09 by Daniel Z. Uslan, Muhammad R Sohail, Jennifer L St Sauver +6 · 28 citations
Arts and Humanities · Health Professions · #Hermeneutics and Narrative Identity #Aging, Elder Care, and Social Issues #Health, Medicine and Society
paper · doi:10.1001/archinte.167.7.669
Abstract
<h3>Background</h3> The incidence of cardiac device infection is not well understood. Bloodstream infection (BSI) in patients with permanent pacemakers or implantable cardioverter-defibrillators (hereafter, defibrillators) may reflect device infection. <h3>Methods</h3> Retrospective, population-based cohort study of all adult patients with cardiac devices who resided in Olmsted County, Minnesota, from 1975 to 2004. The medical linkage-system of the Rochester Epidemiology Project and standardized criteria were used to identify all cases of BSI and device infection. The incidence of device infection was calculated with person-years of follow-up after device implantation. <h3>Results</h3> A total of 1524 patients with cardiac devices were included in the cohort. Total person-time of follow-up was 7578 years. The incidence of definite device infection was 1.9 per 1000 device-years (95% confidence interval [CI], 1.1-3.1). The incidence of pocket infection without BSI was 1.37 per 1000 device-years (95% CI, 0.62-3.05), and pocket infection with BSI or device-related endocarditis 1.14 per 1000 device years (95% CI, 0.47-2.74). The cumulative probability of device infection was higher among patients with defibrillators compared with those with pacemakers,<i>P</i><.001. Twelve (54.6%) of 22 cases of<i>Staphylococcus aureus</i>BSI had definite or possible cardiac device infection vs 3 (12.0%) of 25 cases of bloodstream infection due to gram-negative bacilli (<i>P</i> = .004). <h3>Conclusions</h3> To our knowledge, this is the first population-based study to describe the incidence of cardiac device infection. Device infection was common during episodes of<i>S aureus</i>BSI. The rate of cardiac device infection was higher in patients with defibrillators than in those with pacemakers.
Cited by
- Complication Rates Associated With Pacemaker or Implantable Cardioverter-Defibrillator Generator Replacements and Upgrade Procedures
- Staphylococcus aureus Infections: Epidemiology, Pathophysiology, Clinical Manifestations, and Management
- 2021 ESC Guidelines on cardiac pacing and cardiac resynchronization therapy
- Infection after ICD implantation: operating room versus cardiac catheterisation laboratory. [europepmc]
- New perspectives of infections in cardiovascular disease. [europepmc]
- Permanent pacemaker and implantable cardioverter defibrillator infections: seven years of diagnostic and therapeutic experience of a single center. [europepmc]
- Future challenges and treatment of Staphylococcus aureus bacteremia with emphasis on MRSA. [europepmc]
- Infection after pacemaker implantation: infection rates and risk factors associated with infection in a population-based cohort study of 46299 consecutive patients. [europepmc]
- Use of a simple criteria set for guiding echocardiography in nosocomial Staphylococcus aureus bacteremia. [europepmc]
- Transvenous extraction of pacemaker leads in infective endocarditis with vegetations ≥20 mm: our experience. [europepmc]
- Clinical presentation and outcomes of cardiovascular implantable electronic device infections in hemodialysis patients. [europepmc]
- Combination prophylactic therapy with rifampin increases efficacy against an experimental Staphylococcus epidermidis subcutaneous implant-related infection. [europepmc]
- Staphylococcus aureus infections: epidemiology, pathophysiology, clinical manifestations, and management. [europepmc]
- Cost-Effectiveness of Adding Cardiac Resynchronization Therapy to an Implantable Cardioverter-Defibrillator Among Patients With Mild Heart Failure. [europepmc]
- Patient Report and Review of Rapidly Growing Mycobacterial Infection after Cardiac Device Implantation. [europepmc]
- Implantable Device-Related Infection. [europepmc]
- Management of Cardiac Electronic Device Infections: Challenges and Outcomes. [europepmc]
- Epidemiological and mortality trends in infective endocarditis, a 17-year population-based prospective study. [europepmc]
- Reuse of pacemakers, defibrillators and cardiac resynchronisation devices. [europepmc]
- Repeated procedures at the generator pocket are a determinant of implantable cardioverter-defibrillator infection. [europepmc]
- Imaging infective endocarditis: Adherence to a diagnostic flowchart and direct comparison of imaging techniques. [europepmc]
- European Heart Rhythm Association (EHRA) international consensus document on how to prevent, diagnose, and treat cardiac implantable electronic device infections-endorsed by the Heart Rhythm Society (HRS), the Asia Pacific Heart Rhythm Society (APHRS), the Latin American Heart Rhythm Society (LAHRS), International Society for Cardiovascular Infectious Diseases (ISCVID) and the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS). [europepmc]
- Multimodality Imaging in the Diagnostic Work-Up of Endocarditis and Cardiac Implantable Electronic Device (CIED) Infection. [europepmc]
- Cardiac Electronic Devices: Future Directions and Challenges. [europepmc]
- 2021 ESC Guidelines on cardiac pacing and cardiac resynchronization therapy. [europepmc]
- Infective Endocarditis in High-Income Countries. [europepmc]
- Cardiac Implantable Electronic Devices Infection Assessment, Diagnosis and Management: A Review of the Literature. [europepmc]
- Lifestyle habits associated with cardiac conduction disease. [europepmc]
Related