2020/08/26 by Sugandha Goel, Goel, Sugandha, Isha Gupta +9
Biochemistry, Genetics and Molecular Biology · Medicine · #610 Medical sciences #Amyloidosis: Diagnosis, Treatment, Outcomes #Dermatological and Skeletal Disorders #Medicine #Vascular Tumors and Angiosarcomas #angioid streaks #comet lesions #multicolor imaging
paper · doi:10.3205/oc000165
openalex publication_date 2020/08/26 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/22
Angioid streaks (AS) are irregular crack-like dehiscences in Bruch's membrane that are often associated with atrophic degeneration of the overlying retinal pigment epithelium. We herein report multimodal imaging of AS. Multicolor imaging highlighted AS in dark orange color. AS were better visualized in infrared reflectance as compared to green reflectance and blue reflectance. Peau d'orange appearance was seen as alternating dark and bright patches on color fundus photography with corresponding hyporeflective and hyperreflective patches on infrared reflectance. Comet lesions showed increased signal on infrared reflectance and hyperautofluorescence. Multicolor imaging is a non-invasive imaging modality which helps in clearly delineating these lesions.