GOA-1 regulates spermathecal transits

2025/09/30 by Fereshteh Sadeghian, Virginie Sjoelund, Erin J. Cram
Biochemistry, Genetics and Molecular Biology · #Cellular Mechanics and Interactions #Cellular transport and secretion #Protein Kinase Regulation and GTPase Signaling

paper · doi:10.17912/micropub.biology.001877

openalex publication_date 2025/09/30 · openalex created_date 2025/11/11 · openalex updated_date 2026/07/01

Abstract

spermatheca. In this study, we show that the inhibitory Gαi/o subunit GOA-1 regulates spermathecal transit. We employed TurboID proximity labeling and mass spectrometry to identify 16 candidate interactors of GOA-1 . Depletion of these candidates by RNAi did not yield overt spermathecal transit defects.

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