2016/03/15 by Donny Dwiputra, Dwiputra, Donny, Wahyu Hidayat +3
Biochemistry, Genetics and Molecular Biology · Physics and Astronomy · #Biomolecules (q-bio.BM) #FOS: Biological sciences #FOS: Physical sciences #Pattern Formation and Solitons (nlin.PS) #Soft Condensed Matter (cond-mat.soft) #cond-mat.soft #nlin.PS #q-bio.BM
paper · pdf · doi:10.48550/arxiv.1607.01608
arxiv created 2016/03/15 · arxiv updated 2016/07/07
We propose a dynamical model depicting the interactions between DNA and a specific binding protein involving long range transmissions. The dynamics rely on the coupling between Hydrogen bonds formed between DNA and protein and between the base pairs because they account for site specificity of the binding. We adopt the Morse potential with coupling terms to construct the Hamiltonian. This model gives rise to a breather excitation, corresponding to the DNA bubble formation, which propagates as the carrier of genetic information. We examine the various kind of possible coupling dynamics and suggest the model feasibility in depicting the renaturation or hybridization processes.