2025/02/27 by Brown, Nathaniel K., Depuydt, Lore, Zakeri, Mohsen +8
#Data Structures and Algorithms (cs.DS) #FOS: Computer and information sciences
paper · doi:10.48550/arxiv.2502.20338
Long maximal exact matches (MEMs) are used in many genomics applications such as read classification and sequence alignment. Li's ropebwt3 finds long MEMs quickly because it can often ignore much of its input. In this paper we show that a fast and space efficient k-mer filtration step using a Bloom filter speeds up MEM-finders such as ropebwt3 even further by letting them ignore even more. We also show experimentally that our approach can accelerate metagenomic classification without significantly hurting accuracy.