Differences in Age and Body Site Distribution of the Histological Subtypes of Basal Cell Carcinoma

1997/05/01 by Christopher J. McCormack, Christopher McCormack · 10 citations
Medicine · #Nonmelanoma Skin Cancer Studies #Cancer and Skin Lesions #Cutaneous Melanoma Detection and Management

paper · doi:10.1001/archderm.1997.03890410049006

Abstract

<h3>Objective:</h3> To assess if there are any significant differences in the sex, anatomical site, and age distribution of patients with different histological subtypes of basal cell carcinoma (BCC). <h3>Design:</h3> Histopathology reports were analyzed with respect to the subtype of BCC, site of a tumor, and age and sex of a patient. <h3>Setting:</h3> Histopathology reports were reviewed from 1 private laboratory that derived its cases from general practitioners, surgeons, and dermatologists. <h3>Patients:</h3> Patients with BCC (N=3885) for whom case data were received by the pathology laboratory from January 2, 1991, to June 12, 1991, were included in the study. <h3>Interventions:</h3> None. <h3>Main Outcome Measures:</h3> Superficial BCCs differed from other subtypes of BCC by occurring more commonly on the trunk and in younger patients. <h3>Results:</h3> The mean age (56.8 years) of the patients with superficial BCCs was significantly lower than that of the patients with other subtypes of BCC who were examined (<i>P</i>&lt;.001); the mean ages of the patients with these other subtypes were as follows: nodulosuperficial BCC, 62.9 years; nodular BCC, 63.9 years; nodulomorpheic BCC, 66.1 years; and morpheic BCC, 66.0 years. The majority of superficial BCCs occurred on the trunk and limbs (73.3%), while the majority of all other subtypes occurred on the head and neck. <h3>Conclusions:</h3> Superficial BCC differs from the other subtypes of BCC in terms of patient age and tumor site, and these findings may reflect differences in the etiology. Arch Dermatol. 1997;133:593-596

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