2014/04/14 by E Sato, Alexandre Reily Rocha, Sato, E. T. +7
Biochemistry, Genetics and Molecular Biology · Engineering · Materials Science · #Biological Physics (physics.bio-ph) #Biomolecules (q-bio.BM) #Collagen: Extraction and Characterization #Elasticity and Material Modeling #FOS: Biological sciences #FOS: Physical sciences #Hydrogels: synthesis, properties, applications #Soft Condensed Matter (cond-mat.soft)
paper · pdf · doi:10.48550/arxiv.1404.3449
openalex publication_date 2014/04/14 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28
The present work presents a density-functional microscopic model of soft biological tissue. The model was based on a prototype molecular structure from experimentally resolved collagen peptide residues and water clusters and has the objective to capture some well-known experimental features of soft tissues. It was obtained the optimized geometry, binding and coupling energies and dipole moments. The results concerning the stability of the confined water clusters, the water-water and water-collagen interactions within the CLBM framework were successfully correlated to some important trends observed experimentally in inflammatory tissues.