2020/03/26 by Michael Kresken, Béatrice Grabein, Kresken, Michael +9
Biochemistry, Genetics and Molecular Biology · Medicine · #610 Medical sciences #Antibiotics Pharmacokinetics and Efficacy #Antimicrobial Resistance in Staphylococcus #Bacterial Identification and Susceptibility Testing #Medicine
paper · doi:10.3205/id000062
openalex publication_date 2020/03/26 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/27
updated version. The German guideline by the Paul-Ehrlich-Gesellschaft für Chemotherapie e.V. (PEG) has been translated to address an international audience. Preliminary microbiological findings regarding the patient and their immediate environment are crucial for the calculation of treatment with antibiotics in each case, as well as the resistance situation of the ward on which the patient is being cared for. If such data is not available, regional or supra-regional data can be used as a fallback. This chapter describes the methods of susceptibility testing, informs about the resistance situation in Germany and describes the main resistance mechanisms of bacterial pathogens against antibiotics. Further, the chapter informs about collateral damage of antibiotics as well as medical measures against increasing resistance.