2023/10/14 by T. A. Leatham, D. M. Paganin, Leatham, T. A. +3 · 2 citations
Medicine · Physics and Astronomy · #Advanced Neuroimaging Techniques and Applications #Advanced X-ray Imaging Techniques #FOS: Electrical engineering #FOS: Physical sciences #Image and Video Processing (eess.IV) #MRI in cancer diagnosis #Medical Physics (physics.med-ph) #Optics (physics.optics) #electronic engineering #information engineering
paper · pdf · doi:10.48550/arxiv.2310.09496
openalex publication_date 2023/10/14 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28
X-ray diffusive dark-field imaging, which allows spatially unresolved microstructure to be mapped across a sample, is an increasingly popular tool in an array of settings. Here, we present a new algorithm for phase and dark-field computed tomography based on the x-ray Fokker-Planck equation. Needing only a coherent x-ray source, sample, and detector, our propagation-based algorithm can map the sample density and dark-field/diffusion properties of the sample in 3D. Importantly, incorporating dark-field information in the density reconstruction process enables a higher spatial resolution reconstruction than possible with previous propagation-based approaches. Two sample exposures at each projection angle are sufficient for the successful reconstruction of both the sample density and dark-field Fokker-Planck diffusion coefficients. We anticipate that the proposed algorithm may be of benefit in biomedical imaging and industrial settings.