2009/10/28 by Denis A. Semenov, Semenov, Denis A.
Biochemistry, Genetics and Molecular Biology · #Biomolecules (q-bio.BM) #FOS: Biological sciences #q-bio.BM
paper · pdf · doi:10.48550/arxiv.0910.5371
6 pages, 1 table
arxiv created 2009/10/28 · arxiv updated 2009/12/01
A simple explanation for the symmetry and degeneracy of the genetic code has been suggested. An alternative to the wobble hypothesis has been proposed. This hypothesis offers explanations for: i) the difference between thymine and uracil, ii) encoding of tryptophan by only one codon, iii) why E. coli have no inosine in isoleucine tRNA, but isoleucine is encoded by three codons. The facts revealed in this study offer a new insight into physical mechanisms of the functioning of the genetic code.