A rapid method for the determination of glycogen content and radioactivity in small quantities of tissue or isolated hepatocytes

1976/03/01 by Timothy M. Chan, John H. Exton · 25 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Metabolism and Genetic Disorders #Liver Disease Diagnosis and Treatment #Diet and metabolism studies

paper · doi:10.1016/0003-2697(76)90014-2

Cited by

• Hepatic energy state is regulated by glucagon receptor signaling in mice. [europepmc]
• Endothelial nitric oxide synthase is central to skeletal muscle metabolic regulation and enzymatic signaling during exercise in vivo. [europepmc]
• The adaptor protein APPL1 increases glycogen accumulation in rat skeletal muscle through activation of the PI3-kinase signalling pathway. [europepmc]
• Urocortin 3 transgenic mice exhibit a metabolically favourable phenotype resisting obesity and hyperglycaemia on a high-fat diet. [europepmc]
• Compartmentation of glycogen metabolism revealed from 13C isotopologue distributions. [europepmc]
• A novel mechanism for regulating hepatic glycogen synthesis involving serotonin and cyclin-dependent kinase-5. [europepmc]
• AMP-activated protein kinase (AMPK)α2 plays a role in determining the cellular fate of glucose in insulin-resistant mouse skeletal muscle. [europepmc]
• Urocortin 3 activates AMPK and AKT pathways and enhances glucose disposal in rat skeletal muscle. [europepmc]
• A highly prevalent equine glycogen storage disease is explained by constitutive activation of a mutant glycogen synthase. [europepmc]
• SIRT2 knockout exacerbates insulin resistance in high fat-fed mice. [europepmc]
• Energy metabolism couples hepatocyte integrin-linked kinase to liver glucoregulation and postabsorptive responses of mice in an age-dependent manner. [europepmc]
• A Slow-Digesting Carbohydrate Diet during Rat Pregnancy Protects Offspring from Non-Alcoholic Fatty Liver Disease Risk through the Modulation of the Carbohydrate-Response Element and Sterol Regulatory Element Binding Proteins. [europepmc]
• The Use of Biochemical Measurements to Identify Pre-Slaughter Stress in Pasture Finished Beef Cattle. [europepmc]
• The Impact of Pre-Slaughter Stress on Beef Eating Quality. [europepmc]
• Combinatory high-resolution microdissection/ultra performance liquid chromatographic-mass spectrometry approach for small tissue volume analysis of rat brain glycogen. [europepmc]
• Programming Skeletal Muscle Metabolic Flexibility in Offspring of Male Rats in Response to Maternal Consumption of Slow Digesting Carbohydrates during Pregnancy. [europepmc]
• Maintenance of liver glycogen during long-term fasting preserves energy state in mice. [europepmc]
• Resolution of NASH and hepatic fibrosis by the GLP-1R/GcgR dual-agonist Cotadutide via modulating mitochondrial function and lipogenesis. [europepmc]
• Suppression of glycogen synthesis as a treatment for Lafora disease: Establishing the window of opportunity. [europepmc]
• Peptide-YY 3-36 /glucagon-like peptide-1 combination treatment of obese diabetic mice improves insulin sensitivity associated with recovered pancreatic β-cell function and synergistic activation of discrete hypothalamic and brainstem neuronal circuitries. [europepmc]
• Disrupted liver oxidative metabolism in glycine N-methyltransferase-deficient mice is mitigated by dietary methionine restriction. [europepmc]
• Loss of hepatic phosphoenolpyruvate carboxykinase 1 dysregulates metabolic responses to acute exercise but enhances adaptations to exercise training in mice. [europepmc]
• Exercise training adaptations in liver glycogen and glycerolipids require hepatic AMP-activated protein kinase in mice. [europepmc]
• GLP-1R/GCGR dual agonism dissipates hepatic steatosis to restore insulin sensitivity and rescue pancreatic β-cell function in obese male mice. [europepmc]
• Spatial patterns of hepatocyte glucose flux revealed by stable isotope tracing and multi-scale microscopy. [europepmc]