Facile synthesis of water-soluble and biocompatible fluorescent nitrogen-doped carbon dots for cell imaging

2014/01/01 by Weiping Wang, Ya-Chun Lu, Hong Huang +6 · 13 citations
Materials Science · #Carbon and Quantum Dots Applications #Nanocluster Synthesis and Applications #Luminescence and Fluorescent Materials

paper · doi:10.1039/c3an02098c

Abstract

A simple, facile and green hydrothermal method was developed in the synthesis of water-soluble nitrogen-doped carbon dots (N-CDs) from streptomycin. The as-prepared N-CDs displayed bright blue fluorescence under the irradiation of UV light, together with a high quantum yield of 7.6% and good biocompatibility as demonstrated by the cell viability assay. Thus, the N-CDs can be used as fluorescent probes for cell imaging, which have potential applications in bioimaging and related fields. This strategy opens a new way for the preparation of fluorescent carbon nanomaterials using small molecules as carbon sources.

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