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Seeded iterative clustering for histology region identification

2022/11/14 by Eduard Chelebian, Chelebian, Eduard, Francesco Ciompi +3
Computer Science · Medicine · #AI in cancer detection #Artificial Intelligence (cs.AI) #Cervical Cancer and HPV Research #Computer Vision and Pattern Recognition (cs.CV) #Digital Imaging for Blood Diseases #FOS: Computer and information sciences

paper · pdf · doi:10.48550/arxiv.2211.07425

openalex publication_date 2022/11/14 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28

Abstract

Annotations are necessary to develop computer vision algorithms for histopathology, but dense annotations at a high resolution are often time-consuming to make. Deep learning models for segmentation are a way to alleviate the process, but require large amounts of training data, training times and computing power. To address these issues, we present seeded iterative clustering to produce a coarse segmentation densely and at the whole slide level. The algorithm uses precomputed representations as the clustering space and a limited amount of sparse interactive annotations as seeds to iteratively classify image patches. We obtain a fast and effective way of generating dense annotations for whole slide images and a framework that allows the comparison of neural network latent representations in the context of transfer learning.

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