A carbon dot-based nanoscale covalent organic framework as a new emitter combined with a CRISPR/Cas12a-mediated electrochemiluminescence biosensor for ultrasensitive detection of bisphenol A

2023/01/01 by Rongxian Ma, Jiaxuan Jiang, Yanfei Ya +9 · 7 citations
Biochemistry, Genetics and Molecular Biology · Materials Science · #Advanced biosensing and bioanalysis techniques #Carbon and Quantum Dots Applications #Conducting polymers and applications

paper · doi:10.1039/d3an00024a

Abstract

with a low detection limit of 2.21 fM (S/N = 3) under the optimized conditions. The biosensor demonstrated that CD-COF can be used as an efficient ECL emitter, thus expanding the application field of COFs. In addition, the good stability and specificity of the biosensor enabled the rapid detection of BPA, which will provide valuable insights into promising ultrasensitive ECL biosensors.

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• Newly Developed Electrochemiluminescence Based on Bipolar Electrochemistry for Multiplex Biosensing Applications: A Consolidated Review. [europepmc]
• Advances of Electrochemical and Electrochemiluminescent Sensors Based on Covalent Organic Frameworks. [europepmc]
• Catalytic Ethylene Oligomerization over Imine-Linked Covalent-Organic Frameworks with Coordinative Ni(II) and Cr(III). [europepmc]
• Rational Design of Covalent Organic Frameworks for Enhanced Reticular Electrochemiluminescence and Biosensing Applications. [europepmc]
• Recent advances in aptamer-integrated covalent organic frameworks for electrochemiluminescence detection of emerging pollutants. [europepmc]
• CRISPR-based electrochemiluminescence biosensors: Principles, optimization strategies, and translational challenges - A review of recent progress. [europepmc]

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