Tunable dynamical tissue phantom for laser speckle imaging

2024/04/22 by Soumyajit Sarkar, Sarkar, Soumyajit, Murali, K. +2
Medicine · #FOS: Physical sciences #Medical Physics (physics.med-ph) #Ocular and Laser Science Research #Optical Imaging and Spectroscopy Techniques #Thermoregulation and physiological responses

paper · pdf · doi:10.48550/arxiv.2404.14577

openalex publication_date 2024/04/22 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28

Abstract

We introduce a novel method to design and implement a tunable dynamical tissue phantom for laser speckle-based in-vivo blood flow imaging. This approach relies on Stochastic Differential Equations (SDE) to control a piezoelectric actuator which, upon illuminated with a laser source, generates speckles of pre-defined probability density function and auto-correlation. The validation experiments show that the phantom can generate dynamic speckles that closely replicate both surfaces as well as deep tissue blood flow for a reasonably wide range and accuracy.

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