2024/04/19 by Mary Issac, Isaac, Mary, Andrea Flinchum +3
Biochemistry, Genetics and Molecular Biology · Medicine · #Antibiotic Resistance in Bacteria #FOS: Health sciences #Infections and bacterial resistance #Nosocomial Infections in ICU
paper · doi:10.13023/jah.0503.05
openalex publication_date 2024/04/19 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/01
Introduction: Carbapenem-resistant Enterobacterales (CRE) are considered urgent, antibiotic-resistant threats in the U.S. and are of global concern. Active collaboration between public health authorities and healthcare facilities and providers will be necessary to prevent and contain these organisms. Purpose: To describe the epidemiology of CRE in Kentucky and to discuss challenges and successes with building and sustaining an effective prevention and containment program. Methods: Retrospective descriptive summary of CRE isolates reported by healthcare providers, facilities, and laboratories in Kentucky from 2013 through 2020. Data available from case reporting forms and laboratory testing are summarized. Results: carbapenemase (KPC) was most common (78%). Surveillance and reporting resulted in identification and active investigation of 11 outbreaks of CP-CRE. Implications: There are challenges with developing, implementing, and sustaining a consistent, effective response to identifying, preventing, and containing CRE. Ongoing public health and facility resources will be necessary to prevent and contain antibiotic-resistant threats and other concerning organisms.