2012/02/29 by Luigi Cosentino, L. Coséntino, P. Finocchiaro +9
Medicine · Physics and Astronomy · #Advanced Radiotherapy Techniques #Atomic and Subatomic Physics Research #FOS: Physical sciences #Instrumentation and Detectors (physics.ins-det) #Medical Imaging Techniques and Applications #Medical Physics (physics.med-ph) #Radiation Detection and Scintillator Technologies #physics.ins-det #physics.med-ph
paper · pdf · doi:10.48550/arxiv.1203.0043
18 pages, 20 figures
arxiv created 2012/02/29 · openalex publication_date 2012/02/29 · arxiv updated 2012/03/02 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28
In this paper we prove that the choice of a suitable treatment of the scintillator surfaces, along with suitable photodetectors electronics and specific algorithms for raw data analysis, allow to achieve an optimal tradeoff between energy, time and DOI resolution, thus strongly supporting the feasibility of a prostate TOF- PET probe, MRI compatible, with the required features and performance. In numbers this means a detector element of 1.5mm x 1.5mm x 10mm, achieving at the same time energy resolution around 11.5%, time-of- flight resolution around 150 ps and DOI resolution even below 1 mm. We stress that such a time resolution allows to increase significantly the Noise Equivalent Counting Rate, and consequently improve the image quality and the lesion detection capability. These individual values correspond to the best obtained so far by other groups, but we got all of them simultaneously. In our opinion this proof of principle paves the way to the feasibility of a TOF-PET MRI compatible probe with unprecedented features and performance, not only innovative for prostate radiotracer imaging but possibly also for other organs.