1959/03/21 by Meyer Friedman · 27 citations
Medicine · Psychology · #Anxiety #Cardiology #Cholesterol #Coronary artery disease #Disease #Incidence (geometry) #Internal medicine #Medicine #Physiology #Psychiatry #Psychology #Smoking Behavior and Cessation
paper · doi:10.1001/jama.1959.03000290012005
openalex publication_date 1959/03/21 · openalex created_date 2016/06/24 · openalex updated_date 2026/07/28
Three groups of men, selected solely according to the behavior pattern which they habitually manifested in their work, were compared with respect to their serum cholesterol levels, clotting times, presence of clinical coronary disease, and presence of arcus senilis. A group (A) of 83 men were chosen as manifesting an intense, sustained drive for achievement and as being continually involved in competition and deadlines, both at work and in their avocations. In this group the serum cholesterol level, the frequency of arcus senilis, and the incidence of coronary artery disease were much higher than in a group (B) of 83 men who manifested the opposite sort of behavior pattern and a group (C) of 46 unemployed blind men selected as manifesting a chronic state of insecurity and anxiety. Clinical coronary artery disease was seven times more frequent in group A than in group B or group C. Analysis of factors other than the overt behavior pattern described indicated that this pattern per se was largely responsible for the striking differences found.