1945/05/19 by ALFRED BLALOCK, Alfred Blalock · 20 citations
Medicine · #Business #Cardiac Arrhythmias and Treatments #Cardiology #Congenital Diaphragmatic Hernia Studies #Congenital Heart Disease Studies #Intensive care medicine #Medicine
paper · doi:10.1001/jama.1945.02860200029009
openalex publication_date 1945/05/19 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28
Heretofore there has been no satisfactory treatment for pulmonary stenosis and pulmonary atresia. A "blue" baby with a malformed heart was considered beyond the reach of surgical aid. During the past three months we have operated on 3 children with severe degrees of pulmonary stenosis and each of the patients appears to be greatly benefited. In the second and third cases, in which there was deep persistent cyanosis, the cyanosis has greatly diminished or has disappeared and the general condition of the patients is proportionally improved. The results are sufficiently encouraging to warrant an early report. The operation here reported and the studies leading thereto were undertaken with the conviction that even though the structure of the heart was grossly abnormal, in many instances it might be possible to alter the course of the circulation in such a manner as to lessen the cyanosis and the 'resultant disability. It is