Traumatic Brain Injury and Mitochondrial Dysfunction

2015/06/17 by John B. Hiebert, Qiuhua Shen, Amanda R. Thimmesch +1 · 26 citations
Biochemistry, Genetics and Molecular Biology · Medicine · Neuroscience · #Bioinformatics #Biology #Internal medicine #Medicine #Mitochondrial Function and Pathology #Mitochondrion #Neuroscience #Oxidative stress #Psychiatry #Reactive oxygen species #Traumatic Brain Injury Research #Traumatic Brain Injury and Neurovascular Disturbances #Traumatic brain injury

paper · doi:10.1097/maj.0000000000000506

openalex publication_date 2015/06/17 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/29

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• Role of NMDA Receptor-Mediated Glutamatergic Signaling in Chronic and Acute Neuropathologies. [europepmc]
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• From Mitochondrial Function to Neuroprotection-an Emerging Role for Methylene Blue. [europepmc]
• Systematic Review of Human and Animal Studies Examining the Efficacy and Safety of N- Acetylcysteine (NAC) and N- Acetylcysteine Amide (NACA) in Traumatic Brain Injury: Impact on Neurofunctional Outcome and Biomarkers of Oxidative Stress and Inflammation. [europepmc]
• Ablation of caspase-1 protects against TBI-induced pyroptosis in vitro and in vivo. [europepmc]
• Mitochondrial uncoupling prodrug improves tissue sparing, cognitive outcome, and mitochondrial bioenergetics after traumatic brain injury in male mice. [europepmc]
• Neuroprotective Effect of Artesunate in Experimental Model of Traumatic Brain Injury. [europepmc]
• Testosterone Administration after Traumatic Brain Injury Reduces Mitochondrial Dysfunction and Neurodegeneration. [europepmc]
• Prophylactic treatment of hyperbaric oxygen treatment mitigates inflammatory response via mitochondria transfer. [europepmc]
• Polydatin prevents the induction of secondary brain injury after traumatic brain injury by protecting neuronal mitochondria. [europepmc]
• Long Non-coding RNA in CNS Injuries: A New Target for Therapeutic Intervention. [europepmc]
• Transcriptional activation of antioxidant gene expression by Nrf2 protects against mitochondrial dysfunction and neuronal death associated with acute and chronic neurodegeneration. [europepmc]
• The Potential for Natural Antioxidant Supplementation in the Early Stages of Neurodegenerative Disorders. [europepmc]
• Mitochondria as a target for neuroprotection: role of methylene blue and photobiomodulation. [europepmc]
• Mechanosensation in traumatic brain injury. [europepmc]
• Links between thrombosis and inflammation in traumatic brain injury. [europepmc]
• Glucose metabolism: A link between traumatic brain injury and Alzheimer's disease. [europepmc]
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• Traumatic Brain Injury: Ultrastructural Features in Neuronal Ferroptosis, Glial Cell Activation and Polarization, and Blood-Brain Barrier Breakdown. [europepmc]
• Progress in Understanding Ferroptosis and Its Targeting for Therapeutic Benefits in Traumatic Brain and Spinal Cord Injuries. [europepmc]
• Pyroptosis: A promising therapeutic target for noninfectious diseases. [europepmc]
• Reactive gliosis in traumatic brain injury: a comprehensive review. [europepmc]
• Tufm lactylation regulates neuronal apoptosis by modulating mitophagy in traumatic brain injury. [europepmc]