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Deformable Image Registration of Dark-Field Chest Radiographs for Local Lung Signal Change Assessment

2025/01/18 by Fabian Drexel, Drexel, Fabian, Vasiliki Sideri‐Lampretsa +14
Engineering · Medicine · #Computer Vision and Pattern Recognition (cs.CV) #FOS: Computer and information sciences #FOS: Electrical engineering #FOS: Physical sciences #Image and Video Processing (eess.IV) #Infrared Thermography in Medicine #Medical Physics (physics.med-ph) #Optical Imaging and Spectroscopy Techniques #Photoacoustic and Ultrasonic Imaging #electronic engineering #information engineering

paper · pdf · doi:10.48550/arxiv.2501.10757

openalex publication_date 2025/01/18 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28

Abstract

Dark-field radiography of the human chest has been demonstrated to have promising potential for the analysis of the lung microstructure and the diagnosis of respiratory diseases. However, previous studies of dark-field chest radiographs evaluated the lung signal only in the inspiratory breathing state. Our work aims to add a new perspective to these previous assessments by locally comparing dark-field lung information between different respiratory states. To this end, we discuss suitable image registration methods for dark-field chest radiographs to enable consistent spatial alignment of the lung in distinct breathing states. Utilizing full inspiration and expiration scans from a clinical chronic obstructive pulmonary disease study, we assess the performance of the proposed registration framework and outline applicable evaluation approaches. Our regional characterization of lung dark-field signal changes between the breathing states provides a proof-of-principle that dynamic radiography-based lung function assessment approaches may benefit from considering registered dark-field images in addition to standard plain chest radiographs.

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