2005/09/15 by J. Tothova, Jana Tóthová, B. Brutovský +6
Biochemistry, Genetics and Molecular Biology · Chemistry · Engineering · Physics and Astronomy · #DNA and Nucleic Acid Chemistry #Electrostatics and Colloid Interactions #FOS: Physical sciences #Nanopore and Nanochannel Transport Studies #Soft Condensed Matter (cond-mat.soft) #cond-mat.soft
paper · pdf · doi:10.48550/arxiv.cond-mat/0509399
13 pages
arxiv created 2005/09/15 · openalex publication_date 2005/09/15 · arxiv updated 2009/12/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28
The dynamics of flexible polymers in dilute solution is usually described in terms of the pure Rouse or Zimm bead-spring models assuming continuous distribution of the internal relaxation modes. We show that this approach may lead to misleading interpretation of experimental data. The more correct description should come from the joint Rouse-Zimm (RZ) theory that contains the Rouse and Zimm models as limiting cases. The internal modes are discrete with respect to the mode number, and the type of the bead motion changes in the time from the Rouse to Zimm behavior. We demonstrate this interpreting the recent first observation of the kinetics of individual polymer monomers using the fluorescence correlation technique [R. Shusterman et al., Phys. Rev. Lett. 92, 048303 (2004)]. Optimizing the RZ theory to the data on double- and single-stranded DNA coils (dsDNA and ssDNA) the parameters for the statistical-mechanical description of the behavior of these polymers have been determined. The calculations indicate that dsDNA follows mainly the classical Zimm-type kinetics rather than the Rouse one as it was originally proposed. Single-stranded DNA also behaves predominantly as the Zimm polymer. For dsDNA the Kuhn length agrees with the commonly accepted value in the literature while in the case of ssDNA it takes a value much larger than it is usually cited in the literature.