2021/11/28 by Dhwanit Agarwal, Agarwal, Dhwanit, George Biros +1
Chemical Engineering · Medicine · #Blood properties and coagulation #Erythrocyte Function and Pathophysiology #FOS: Physical sciences #Fluid Dynamics (physics.flu-dyn) #Rheology and Fluid Dynamics Studies #Soft Condensed Matter (cond-mat.soft)
paper · pdf · doi:10.48550/arxiv.2111.14206
openalex publication_date 2021/11/28 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28
We use numerical simulations to study the dynamics of red blood cells (RBCs) in unconfined and confined Poiseuille flow. Previous numerical studies with 3D vesicles have indicated that the slipper shape observed in experiments at high capillary number can be attributed to the bistability due to the interplay of wall push and outward migration tendency at higher viscosity contrasts. In this paper, we study this outward migration and bistability using numerical simulations for 3D capsules and provide phase diagrams of RBC dynamics with and without viscosity contrast. We observe a bistability of slipper and croissants in confined Poiseuille flow with viscosity contrast as observed in experiments.