2006/03/30 by Otger Campas, Otger Campàs, Jaume Casademunt +4
Biochemistry, Genetics and Molecular Biology · Computer Science · Physics and Astronomy · #Biological Physics (physics.bio-ph) #FOS: Biological sciences #FOS: Physical sciences #Microtubule and mitosis dynamics #Nonlinear Dynamics and Pattern Formation #Protein Structure and Dynamics #Subcellular Processes (q-bio.SC) #physics.bio-ph #q-bio.SC
paper · pdf · doi:10.48550/arxiv.q-bio/0603036
4 pages, 3 figures
arxiv created 2006/03/30 · openalex publication_date 2006/03/30 · arxiv updated 2009/12/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28
We analyze the role of the force-dependent kinetics of motor proteins in the stability of antiparallel arrays of polar filaments, such as those in the mitotic spindle. We determine the possible stable structures and show that there exists an instability associated to the collective behavior of motors that leads to the collapse of the spindle. Our analysis provides a general framework to understand several experimental observations in eukaryotic cell division.