2015/05/08 by Larry Bull, Bull, Larry · 1 citation
Biochemistry, Genetics and Molecular Biology · Computer Science · #FOS: Biological sciences #FOS: Computer and information sciences #Molecular Networks (q-bio.MN) #Neural and Evolutionary Computing (cs.NE) #Populations and Evolution (q-bio.PE) #cs.NE #q-bio.MN #q-bio.PE
paper · pdf · doi:10.48550/arxiv.1505.01980
arXiv admin note: substantial text overlap with arXiv:1306.4793, arXiv:1303.7220
arxiv created 2015/05/08 · arxiv updated 2015/05/11
The editing of transcribed RNA by other molecules such that the form of the final product differs from that specified in the corresponding DNA sequence is ubiquitous. This paper uses an abstract, tunable Boolean genetic regulatory network model to explore aspects of RNA editing. In particular, it is shown how dynamically altering expressed sequences via a guide RNA-inspired mechanism can be selected for by simulated evolution under various single and multicellular scenarios.