2025/08/07 by Nasterlack, Michael, Walter, Dirk, Drexler, Hans +2
#571.95 Toxicology #571.95 Toxikologie #616.9803 Betriebs- und Arbeitsmedizin #616.9803 Industrial and occupational medicine #Arbeitsstoff #Beurteilungswert #Biomonitoring #EKA #Expositionsäquivalente für krebserzeugende Arbeitsstoffe #Gefahrstoff #Nickel #Nickel carbonate #Nickel oxide #Nickel sulfide #Nickelcarbonat #Nickeloxid #Nickelsulfid #Sulfidic ores (nickel) #Sulfidische Erze (Nickel) #Toxizität #Urin #assessment value #berufliche Exposition #biomonitoring #exposure equivalents for carcinogenic substances #hazardous substance #occupational exposure #substance in the work area #toxicity #urine
paper · doi:10.34865/bb744002verd0024_w
In 2018 the German Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area has re‐evaluated the correlation (EKA) between inhalational exposure to nickel and sparingly soluble nickel compounds (nickel as nickel metal, nickel sulphide, sulphidic ores, nickel oxide, nickel carbonate) and urinary nickel excretion. The update and evaluation of the available literature led to the conclusion that the EKA correlation could be confirmed for exposures in the range between 100 and 500 µg Ni/m3. An extrapolation of the regression equation to the low dose range turned out to be impossible for both formal and practical reasons.