2016/12/01 by Joseph Antonelli, Antonelli, Joseph, Matthew Cefalu +5 · 1 citation
Economics, Econometrics and Finance · Mathematics · #Advanced Causal Inference Techniques #FOS: Computer and information sciences #Health Systems, Economic Evaluations, Quality of Life #Healthcare Policy and Management #Methodology (stat.ME)
paper · pdf · doi:10.48550/arxiv.1612.00424
openalex publication_date 2016/12/01 · openalex created_date 2022/10/06 · openalex updated_date 2026/07/28
Valid estimation of treatment effects from observational data requires proper\ncontrol of confounding. If the number of covariates is large relative to the\nnumber of observations, then controlling for all available covariates is\ninfeasible. In cases where a sparsity condition holds, variable selection or\npenalization can reduce the dimension of the covariate space in a manner that\nallows for valid estimation of treatment effects. In this article, we propose\nmatching on both the estimated propensity score and the estimated prognostic\nscores when the number of covariates is large relative to the number of\nobservations. We derive asymptotic results for the matching estimator and show\nthat it is doubly robust, in the sense that only one of the two score models\nneed be correct to obtain a consistent estimator. We show via simulation its\neffectiveness in controlling for confounding and highlight its potential to\naddress nonlinear confounding. Finally, we apply the proposed procedure to\nanalyze the effect of gender on prescription opioid use using insurance claims\ndata.\n