2003/03/12 by caterina Guiot, Caterina Guiot, Piero Giorgio Degiorgis +9
Biochemistry, Genetics and Molecular Biology · Mathematics · Physics and Astronomy · #Cancer Genomics and Diagnostics #Cancer, Hypoxia, and Metabolism #FOS: Biological sciences #FOS: Physical sciences #Mathematical Biology Tumor Growth #Medical Physics (physics.med-ph) #Quantitative Biology (q-bio) #physics.med-ph #q-bio
paper · pdf · doi:10.48550/arxiv.physics/0303050
arxiv created 2003/03/12 · openalex publication_date 2003/03/12 · arxiv updated 2009/12/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28
A general model for the ontogenetic growth of living organisms has been recently proposed. Here we investigate the extension of this model to the growth of solid malignant tumors. A variety of in vitro and in vivo data are analyzed and compared with the prediction of a 'universal' law, relating properly rescaled tumor masses and tumor growth times. The results support the notion that tumor growth follows such a universal law. Several important implications of this finding are discussed, including its relevance for tumor metastasis and recurrence, cell turnover rates, angiogenesis and invasion.