2021/05/16 by Alex Gustschin, Gustschin, Alex, Mirko Riedel +23 · 3 citations
Physics and Astronomy · Medicine · #Advanced X-ray Imaging Techniques #Advanced MRI Techniques and Applications
paper · pdf · doi:10.48550/arxiv.2105.07347
Two-dimensional Talbot array illuminators (TAIs) were designed, fabricated,\nand evaluated for high-resolution high-contrast x-ray phase imaging of soft\ntissue at 10-20keV. The TAIs create intensity modulations with a high\ncompression ratio on the micrometer scale at short propagation distances. Their\nperformance was compared with various other wavefront markers in terms of\nperiod, visibility, flux efficiency and flexibility to be adapted for limited\nbeam coherence and detector resolution. Differential x-ray phase contrast and\ndark-field imaging were demonstrated with a one-dimensional, linear phase\nstepping approach yielding two-dimensional phase sensitivity using Unified\nModulated Pattern Analysis (UMPA) for phase retrieval. The method was employed\nfor x-ray phase computed tomography reaching a resolution of 3\μm on an\nunstained murine artery. It opens new possibilities for three-dimensional,\nnon-destructive, and quantitative imaging of soft matter such as virtual\nhistology. The phase modulators can also be used for various other x-ray\napplications such as dynamic phase imaging, super-resolution structured\nillumination microscopy, or wavefront sensing.\n