Expression of The Embryonic Stem Cell Transcription Factor SOX2 in Human Skin

2009/12/30 by Alvaro C. Laga, Chiou-Yan Lai, Qian Zhan +8 · 25 citations
Agricultural and Biological Sciences · Medicine · #Biology #Cancer research #Cell biology #Computational biology #Embryonic stem cell #Gene #Genetics #Plant Virus Research Studies #Polyomavirus and related diseases #SOX2 #Stem cell #Transcription factor #Tumors and Oncological Cases

paper · pdf · doi:10.2353/ajpath.2010.090495

openalex publication_date 2009/12/30 · openalex created_date 2016/06/24 · openalex updated_date 2026/08/04

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• Sox2 protein expression is an independent poor prognostic indicator in stage I lung adenocarcinoma. [europepmc]
• SOX2 and nestin expression in human melanoma: an immunohistochemical and experimental study. [europepmc]
• SOX2 contributes to melanoma cell invasion. [europepmc]
• SOX2 modulates levels of MITF in normal human melanocytes, and melanoma lines in vitro. [europepmc]
• Progression of cutaneous melanoma: implications for treatment. [europepmc]
• Distinct gene expression profiles of viral- and nonviral-associated merkel cell carcinoma revealed by transcriptome analysis. [europepmc]
• The sox family of transcription factors: versatile regulators of stem and progenitor cell fate. [europepmc]
• Stem cells and targeted approaches to melanoma cure. [europepmc]
• SOX2 expression in the developing, adult, as well as, diseased prostate. [europepmc]
• Merkel cell carcinoma expresses vasculogenic mimicry: demonstration in patients and experimental manipulation in xenografts. [europepmc]
• Sox2 acts as a rheostat of epithelial to mesenchymal transition during neural crest development. [europepmc]
• Nestin depletion induces melanoma matrix metalloproteinases and invasion. [europepmc]
• Characterization of Cancer Stem Cells in Moderately Differentiated Buccal Mucosal Squamous Cell Carcinoma. [europepmc]
• Characterization of Cancer Stem Cells in Colon Adenocarcinoma Metastasis to the Liver. [europepmc]
• SOX2 as a novel contributor of oxidative metabolism in melanoma cells. [europepmc]
• SOX2 in cancer stemness: tumor malignancy and therapeutic potentials. [europepmc]
• Conversion of Sox2-dependent Merkel cell carcinoma to a differentiated neuron-like phenotype by T antigen inhibition. [europepmc]
• SOX2 antagonizes WWC1 to drive YAP1 activation in esophageal squamous cell carcinoma. [europepmc]
• Merkel Cell Polyomavirus and Merkel Cell Carcinoma. [europepmc]
• Merkel Cell Polyomavirus T Antigens Induce Merkel Cell-Like Differentiation in GLI1-Expressing Epithelial Cells. [europepmc]
• Downregulation of SOX2 by inhibition of Usp9X induces apoptosis in melanoma. [europepmc]
• Genomic evidence suggests that cutaneous neuroendocrine carcinomas can arise from squamous dysplastic precursors. [europepmc]
• Mitochondrial Metabolism in Melanoma. [europepmc]
• Merkel Cell Polyomavirus: Oncogenesis in a Stable Genome. [europepmc]
• Merkel cell carcinoma: updates in tumor biology, emerging therapies, and preclinical models. [europepmc]