Craniopharyngiomas of Adamantinomatous Type Harbor β-Catenin Gene Mutations

2002/12/01 by Shigeki Sekine, Tatsuhiro Shibata, Akiko Kokubu +5 · 26 citations
Medicine · Biochemistry, Genetics and Molecular Biology · #Pituitary Gland Disorders and Treatments #Hedgehog Signaling Pathway Studies #Neurofibromatosis and Schwannoma Cases

paper · pdf · doi:10.1016/s0002-9440(10)64477-x

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• Diagnosis and management of children and adult craniopharyngiomas: A French Endocrine Society/French Society for Paediatric Endocrinology & Diabetes Consensus Statement
• The Wnt signaling pathway and its role in tumor development. [europepmc]
• Pituitary tumors in childhood: update of diagnosis, treatment and molecular genetics. [europepmc]
• Wnt/beta-catenin signaling in oral tissue development and disease. [europepmc]
• Identification of novel pathways involved in the pathogenesis of human adamantinomatous craniopharyngioma. [europepmc]
• Craniopharyngioma in adults. [europepmc]
• Treatment strategies in childhood craniopharyngioma. [europepmc]
• Exome sequencing identifies BRAF mutations in papillary craniopharyngiomas. [europepmc]
• BRAF V600E mutations are characteristic for papillary craniopharyngioma and may coexist with CTNNB1-mutated adamantinomatous craniopharyngioma. [europepmc]
• Molecular and cellular pathogenesis of adamantinomatous craniopharyngioma. [europepmc]
• Identification of targets for rational pharmacological therapy in childhood craniopharyngioma. [europepmc]
• ENDOCRINE TUMORS: BRAF V600E mutations in papillary craniopharyngioma. [europepmc]
• Stem cell senescence drives age-attenuated induction of pituitary tumours in mouse models of paediatric craniopharyngioma. [europepmc]
• Multiplexed immunofluorescence reveals potential PD-1/PD-L1 pathway vulnerabilities in craniopharyngioma. [europepmc]
• Rathke's Cleft Cyst as Origin of a Pediatric Papillary Craniopharyngioma. [europepmc]
• Practical implementation of DNA methylation and copy-number-based CNS tumor diagnostics: the Heidelberg experience. [europepmc]
• Noninvasive molecular diagnosis of craniopharyngioma with MRI-based radiomics approach. [europepmc]
• SHH pathway inhibition is protumourigenic in adamantinomatous craniopharyngioma. [europepmc]
• Targeting IL-6 Is a Potential Treatment for Primary Cystic Craniopharyngioma. [europepmc]
• Beta-Catenin Causes Adrenal Hyperplasia by Blocking Zonal Transdifferentiation. [europepmc]
• Diagnosis, Background, and Treatment of Hypothalamic Damage in Craniopharyngioma. [europepmc]
• A pediatric brain tumor atlas of genes deregulated by somatic genomic rearrangement. [europepmc]
• Adamantinomatous craniopharyngioma as a model to understand paracrine and senescence-induced tumourigenesis. [europepmc]
• Intertwined Signaling Pathways Governing Tooth Development: A Give-and-Take Between Canonical Wnt and Shh. [europepmc]
• Characterization of novel CTNNB1 mutation in Craniopharyngioma by whole-genome sequencing. [europepmc]
• OpenPBTA: The Open Pediatric Brain Tumor Atlas. [europepmc]