Craniopharyngiomas of Adamantinomatous Type Harbor β-Catenin Gene Mutations

2002/12/01 by Shigeki Sekine, Tatsuhiro Shibata, Akiko Kokubu +5 · 306 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Biology #Computational biology #Gene #Genetics #Hedgehog Signaling Pathway Studies #Medicine #Neurofibromatosis and Schwannoma Cases #Pathology #Pituitary Gland Disorders and Treatments

paper · pdf · doi:10.1016/s0002-9440(10)64477-x

published in American Journal Of Pathology 161(6), 1997-2001 (Elsevier BV)

openalex publication_date 2002/12/01 · openalex created_date 2016/06/24 · openalex updated_date 2026/07/29

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• Treatment strategies in childhood craniopharyngioma. [europepmc]
• Exome sequencing identifies BRAF mutations in papillary craniopharyngiomas. [europepmc]
• BRAF V600E mutations are characteristic for papillary craniopharyngioma and may coexist with CTNNB1-mutated adamantinomatous craniopharyngioma. [europepmc]
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• ENDOCRINE TUMORS: BRAF V600E mutations in papillary craniopharyngioma. [europepmc]
• Stem cell senescence drives age-attenuated induction of pituitary tumours in mouse models of paediatric craniopharyngioma. [europepmc]
• Multiplexed immunofluorescence reveals potential PD-1/PD-L1 pathway vulnerabilities in craniopharyngioma. [europepmc]
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• Practical implementation of DNA methylation and copy-number-based CNS tumor diagnostics: the Heidelberg experience. [europepmc]
• Noninvasive molecular diagnosis of craniopharyngioma with MRI-based radiomics approach. [europepmc]
• SHH pathway inhibition is protumourigenic in adamantinomatous craniopharyngioma. [europepmc]
• Targeting IL-6 Is a Potential Treatment for Primary Cystic Craniopharyngioma. [europepmc]
• Beta-Catenin Causes Adrenal Hyperplasia by Blocking Zonal Transdifferentiation. [europepmc]
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• Adamantinomatous craniopharyngioma as a model to understand paracrine and senescence-induced tumourigenesis. [europepmc]
• Intertwined Signaling Pathways Governing Tooth Development: A Give-and-Take Between Canonical Wnt and Shh. [europepmc]
• Characterization of novel CTNNB1 mutation in Craniopharyngioma by whole-genome sequencing. [europepmc]
• OpenPBTA: The Open Pediatric Brain Tumor Atlas. [europepmc]