Alternatively Activated Macrophages and Collagen Remodeling Characterize the Postpartum Involuting Mammary Gland across Species

2010/01/28 by Jenean O'Brien, Jenean O’Brien, Traci Lyons +11 · 26 citations
Medicine · Immunology and Microbiology · #Mesenchymal stem cell research #Reproductive System and Pregnancy #Cancer Risks and Factors

paper · pdf · doi:10.2353/ajpath.2010.090735

Citations

• Remodeling of the Mammary Microenvironment after Lactation Promotes Breast Tumor Cell Metastasis

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• Aligned Collagen Is a Prognostic Signature for Survival in Human Breast Carcinoma
• Human gingiva-derived mesenchymal stem cells elicit polarization of m2 macrophages and enhance cutaneous wound healing. [europepmc]
• LOXL2-mediated matrix remodeling in metastasis and mammary gland involution. [europepmc]
• Postpartum mammary gland involution drives progression of ductal carcinoma in situ through collagen and COX-2. [europepmc]
• Why the stroma matters in breast cancer: insights into breast cancer patient outcomes through the examination of stromal biomarkers. [europepmc]
• Interleukin-4- and interleukin-13-mediated alternatively activated macrophages: roles in homeostasis and disease. [europepmc]
• Postpartum diagnosis demonstrates a high risk for metastasis and merits an expanded definition of pregnancy-associated breast cancer. [europepmc]
• Periodontal disease immunology: 'double indemnity' in protecting the host. [europepmc]
• Collagen architecture in pregnancy-induced protection from breast cancer. [europepmc]
• MerTK inhibition in tumor leukocytes decreases tumor growth and metastasis. [europepmc]
• Cyclooxygenase-2-dependent lymphangiogenesis promotes nodal metastasis of postpartum breast cancer. [europepmc]
• Wound healing-like immune program facilitates postpartum mammary gland involution and tumor progression. [europepmc]
• Efferocytosis produces a prometastatic landscape during postpartum mammary gland involution. [europepmc]
• Biology of breast cancer in young women. [europepmc]
• COX-2 modulates mammary tumor progression in response to collagen density. [europepmc]
• Quantitative extracellular matrix proteomics to study mammary and liver tissue microenvironments. [europepmc]
• Macrophages orchestrate breast cancer early dissemination and metastasis. [europepmc]
• Diverse Functions of Macrophages in Different Tumor Microenvironments. [europepmc]
• Association Between Postpartum Breast Cancer Diagnosis and Metastasis and the Clinical Features Underlying Risk. [europepmc]
• Single cell RNA sequencing identifies unique inflammatory airspace macrophage subsets. [europepmc]
• The role of collagen in cancer: from bench to bedside. [europepmc]
• Cancer Extracellular Matrix Proteins Regulate Tumour Immunity. [europepmc]
• Macrophage Reprogramming and Cancer Therapeutics: Role of iNOS-Derived NO. [europepmc]
• Immune Modulatory Properties of Collagen in Cancer. [europepmc]
• Remodeling the tumor microenvironment via blockade of LAIR-1 and TGF-β signaling enables PD-L1-mediated tumor eradication. [europepmc]
• The Mammary Gland: Basic Structure and Molecular Signaling during Development. [europepmc]