Visualization of severe acute respiratory syndrome coronavirus 2 invading the human placenta using electron microscopy

2020/05/13 by Gabriela N. Algarroba, Patricia Rekawek, Sevan A. Vahanian +6 · 26 citations
Medicine · #COVID-19 Impact on Reproduction #Pregnancy and preeclampsia studies #Maternal and fetal healthcare

paper · pdf · doi:10.1016/j.ajog.2020.05.023

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• Evidence and possible mechanisms of rare maternal-fetal transmission of SARS-CoV-2. [europepmc]
• Transplacental transmission of SARS-CoV-2 infection. [europepmc]
• A Message from the Human Placenta: Structural and Immunomodulatory Defense against SARS-CoV-2. [europepmc]
• Vertical transmission of coronavirus disease 2019: a systematic review and meta-analysis. [europepmc]
• Placental barrier against COVID-19. [europepmc]
• Expression of severe acute respiratory syndrome coronavirus 2 cell entry genes, angiotensin-converting enzyme 2 and transmembrane protease serine 2, in the placenta across gestation and at the maternal-fetal interface in pregnancies complicated by preterm birth or preeclampsia. [europepmc]
• Consistent localization of SARS-CoV-2 spike glycoprotein and ACE2 over TMPRSS2 predominance in placental villi of 15 COVID-19 positive maternal-fetal dyads. [europepmc]
• A structured review of placental morphology and histopathological lesions associated with SARS-CoV-2 infection. [europepmc]
• Hunting coronavirus by transmission electron microscopy - a guide to SARS-CoV-2-associated ultrastructural pathology in COVID-19 tissues. [europepmc]
• Innate Immune Mechanisms to Protect Against Infection at the Human Decidual-Placental Interface. [europepmc]
• Coronavirus disease 2019 and first-trimester spontaneous abortion: a case-control study of 225 pregnant patients. [europepmc]
• Analysis of SARS-CoV-2 vertical transmission during pregnancy. [europepmc]
• Synthesis and systematic review of reported neonatal SARS-CoV-2 infections. [europepmc]
• Coronavirus disease 2019 infection and placental histopathology in women delivering at term. [europepmc]
• Age-determined expression of priming protease TMPRSS2 and localization of SARS-CoV-2 in lung epithelium. [europepmc]
• Placental Pathology of COVID-19 with and without Fetal and Neonatal Infection: Trophoblast Necrosis and Chronic Histiocytic Intervillositis as Risk Factors for Transplacental Transmission of SARS-CoV-2. [europepmc]
• A comprehensive review of the impact of COVID-19 on human reproductive biology, assisted reproduction care and pregnancy: a Canadian perspective. [europepmc]
• Priming of SARS-CoV-2 S protein by several membrane-bound serine proteinases could explain enhanced viral infectivity and systemic COVID-19 infection. [europepmc]
• The Effects of COVID-19 on Placenta and Pregnancy: What Do We Know So Far? [europepmc]
• Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2): a Systemic Infection. [europepmc]
• Severe SARS-CoV-2 placenta infection can impact neonatal outcome in the absence of vertical transmission. [europepmc]
• Haemostatic and thrombo-embolic complications in pregnant women with COVID-19: a systematic review and critical analysis. [europepmc]
• Fetal and placental infection with SARS-CoV-2 in early pregnancy. [europepmc]
• Pregnancy and viral infections: Mechanisms of fetal damage, diagnosis and prevention of neonatal adverse outcomes from cytomegalovirus to SARS-CoV-2 and Zika virus. [europepmc]
• Maternal outcomes and risk factors for COVID-19 severity among pregnant women. [europepmc]