Estimation of SNP Heritability from Dense Genotype Data

2013/12/01 by S. Hong Lee, Sang Lee, Jian Yang +16 · 27 citations
Biochemistry, Genetics and Molecular Biology · #Genetic and phenotypic traits in livestock #Cancer-related molecular mechanisms research #Genetic Mapping and Diversity in Plants and Animals

paper · pdf · doi:10.1016/j.ajhg.2013.10.015

Citations

• Improved Heritability Estimation from Genome-wide SNPs
• GCTA: A Tool for Genome-wide Complex Trait Analysis

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• Behavioural genetics [wikipedia]
• Conditions for the validity of SNP-based heritability estimation. [europepmc]
• Estimating heritability of complex traits from genome-wide association studies using IBS-based Haseman-Elston regression. [europepmc]
• Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases. [europepmc]
• Trans-ethnic genome-wide association studies: advantages and challenges of mapping in diverse populations. [europepmc]
• Genomic heritability: what is it? [europepmc]
• Genetic variance estimation with imputed variants finds negligible missing heritability for human height and body mass index. [europepmc]
• Contrasting genetic architectures of schizophrenia and other complex diseases using fast variance-components analysis. [europepmc]
• The contribution of rare variation to prostate cancer heritability. [europepmc]
• Developing and evaluating polygenic risk prediction models for stratified disease prevention. [europepmc]
• Genome-wide association study of behavioral, physiological and gene expression traits in outbred CFW mice. [europepmc]
• Genetic Analysis of Venous Thromboembolism in UK Biobank Identifies the ZFPM2 Locus and Implicates Obesity as a Causal Risk Factor. [europepmc]
• Phenome-wide heritability analysis of the UK Biobank. [europepmc]
• Reevaluation of SNP heritability in complex human traits. [europepmc]
• Polygenic risk score analysis of pathologically confirmed Alzheimer disease. [europepmc]
• Linkage disequilibrium-dependent architecture of human complex traits shows action of negative selection. [europepmc]
• Heritability of Atrial Fibrillation. [europepmc]
• Comparison of methods that use whole genome data to estimate the heritability and genetic architecture of complex traits. [europepmc]
• Functional architecture of low-frequency variants highlights strength of negative selection across coding and non-coding annotations. [europepmc]
• Quantification of frequency-dependent genetic architectures in 25 UK Biobank traits reveals action of negative selection. [europepmc]
• Genotype-covariate correlation and interaction disentangled by a whole-genome multivariate reaction norm model. [europepmc]
• Accurate estimation of SNP-heritability from biobank-scale data irrespective of genetic architecture. [europepmc]
• Generalized meta-analysis for multiple regression models across studies with disparate covariate information. [europepmc]
• Statistical methods for SNP heritability estimation and partition: A review. [europepmc]
• Theoretical and empirical quantification of the accuracy of polygenic scores in ancestry divergent populations. [europepmc]
• CORE GREML for estimating covariance between random effects in linear mixed models for complex trait analyses. [europepmc]