Optimal Unified Approach for Rare-Variant Association Testing with Application to Small-Sample Case-Control Whole-Exome Sequencing Studies

2012/08/01 by Seunggeun Lee, Mary J. Emond, Michael J. Bamshad +8 · 1,158 citations
Biochemistry, Genetics and Molecular Biology · Mathematics · Psychology · #Association (psychology) #Association test #Biology #Computational biology #Computer science #Data mining #Exome #Exome sequencing #Genetic Associations and Epidemiology #Genetic association #Genetics #Genomic variations and chromosomal abnormalities #Genomics and Rare Diseases #Genotype #Mathematics #Phenotype #Psychology #Sample size determination #Single-nucleotide polymorphism #Statistical power #Statistics #Type I and type II errors

paper · pdf · doi:10.1016/j.ajhg.2012.06.007

published in The American Journal of Human Genetics 91(2), 224-237 (Elsevier BV)

openalex publication_date 2012/08/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/04

Citations

• Generalized Genomic Distance–Based Regression Methodology for Multilocus Association Analysis

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