Linkage, Association, and Gene-Expression Analyses Identify CNTNAP2 as an Autism-Susceptibility Gene

2008/01/01 by Maricela Alarcón, Brett S. Abrahams, Jennifer Stone +11 · 29 citations
Neuroscience · Medicine · Biochemistry, Genetics and Molecular Biology · #Autism Spectrum Disorder Research #Virology and Viral Diseases #Genetics and Neurodevelopmental Disorders

paper · pdf · doi:10.1016/j.ajhg.2007.09.005

Cited by

• A failure of left temporal cortex to specialize for language is an early emerging and fundamental property of autism
• Advances in Autism
• Development of Patient-Specific Neurons in Schizophrenia Using Induced Pluripotent Stem Cells
• Molecular networks of the FOXP2 transcription factor in the brain
• Advances in autism genetics: on the threshold of a new neurobiology. [europepmc]
• Identifying autism loci and genes by tracing recent shared ancestry. [europepmc]
• A functional genetic link between distinct developmental language disorders. [europepmc]
• Autism spectrum disorders and childhood-onset schizophrenia: clinical and biological contributions to a relation revisited. [europepmc]
• Common genetic variants on 5p14.1 associate with autism spectrum disorders. [europepmc]
• Autism genome-wide copy number variation reveals ubiquitin and neuronal genes. [europepmc]
• Genome-wide analyses of exonic copy number variants in a family-based study point to novel autism susceptibility genes. [europepmc]
• Advances in autism. [europepmc]
• Evolution of the neocortex: a perspective from developmental biology. [europepmc]
• A genome-wide linkage and association scan reveals novel loci for autism. [europepmc]
• Genetic overlap between autism, schizophrenia and bipolar disorder. [europepmc]
• Genome-wide copy number variation in epilepsy: novel susceptibility loci in idiopathic generalized and focal epilepsies. [europepmc]
• Investigations of caspr2, an autoantigen of encephalitis and neuromyotonia. [europepmc]
• Maternal infection and immune involvement in autism. [europepmc]
• Exome sequencing in sporadic autism spectrum disorders identifies severe de novo mutations. [europepmc]
• Transcriptomic analysis of autistic brain reveals convergent molecular pathology. [europepmc]
• Genetics of autism spectrum disorders. [europepmc]
• Absence of CNTNAP2 leads to epilepsy, neuronal migration abnormalities, and core autism-related deficits. [europepmc]
• Individual common variants exert weak effects on the risk for autism spectrum disorders. [europepmc]
• A high-coverage genome sequence from an archaic Denisovan individual. [europepmc]
• Cerebral asymmetry and language development: cause, correlate, or consequence? [europepmc]
• Disentangling the heterogeneity of autism spectrum disorder through genetic findings. [europepmc]
• Common mechanisms of excitatory and inhibitory imbalance in schizophrenia and autism spectrum disorders. [europepmc]
• Gene hunting in autism spectrum disorder: on the path to precision medicine. [europepmc]
• Revealing the structure of pharmacobehavioral space through motion sequencing. [europepmc]