Mutation in WNT10A Is Associated with an Autosomal Recessive Ectodermal Dysplasia: The Odonto-onycho-dermal Dysplasia

2007/09/07 by Lynn Adaimy, Eliane Chouery, Éliane Chouery +7 · 27 citations
Biochemistry, Genetics and Molecular Biology · #dental development and anomalies #Wnt/β-catenin signaling in development and cancer #Fibroblast Growth Factor Research

paper · pdf · doi:10.1086/520064

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• Web-based, participant-driven studies yield novel genetic associations for common traits. [europepmc]
• Genetic pathways in disorders of epidermal differentiation. [europepmc]
• Wnt activation in nail epithelium couples nail growth to digit regeneration. [europepmc]
• Candidate gene analysis of tooth agenesis identifies novel mutations in six genes and suggests significant role for WNT and EDA signaling and allele combinations. [europepmc]
• Developmental disorders of the dentition: an update. [europepmc]
• Distinct functions for Wnt/β-catenin in hair follicle stem cell proliferation and survival and interfollicular epidermal homeostasis. [europepmc]
• To grow or not to grow: hair morphogenesis and human genetic hair disorders. [europepmc]
• Wnt and the Wnt signaling pathway in bone development and disease. [europepmc]
• The WNT10A gene in ectodermal dysplasias and selective tooth agenesis. [europepmc]
• Wnt/β-Catenin Regulates the Activity of Epiprofin/Sp6, SHH, FGF, and BMP to Coordinate the Stages of Odontogenesis. [europepmc]
• Mutations in TSPEAR, Encoding a Regulator of Notch Signaling, Affect Tooth and Hair Follicle Morphogenesis. [europepmc]
• Genetic prediction of male pattern baldness. [europepmc]
• Molecular genetics and targeted therapy of WNT-related human diseases (Review). [europepmc]
• Whole-Exome Sequencing Identifies Novel Variants for Tooth Agenesis. [europepmc]
• The Changing Landscape in the Genetic Etiology of Human Tooth Agenesis. [europepmc]
• Role of β-Catenin Activation Levels and Fluctuations in Controlling Cell Fate. [europepmc]
• Pathophysiology of pachyonychia congenita-associated palmoplantar keratoderma: new insights into skin epithelial homeostasis and avenues for treatment. [europepmc]
• WNT Signaling in Disease. [europepmc]
• Wnt Pathway: An Integral Hub for Developmental and Oncogenic Signaling Networks. [europepmc]
• A genetic model for the secretory stage of dental enamel formation. [europepmc]