Pfcrmp May Play a Key Role in Chloroquine Antimalarial Action and Resistance Development

2015/11/27 by Gao-De Li, Li, Gao-De
Computer Science · Medicine · Pharmacology, Toxicology and Pharmaceutics · #Computational Drug Discovery Methods #Drug-Induced Hepatotoxicity and Protection #FOS: Biological sciences #Genomics (q-bio.GN) #Malaria Research and Control #Subcellular Processes (q-bio.SC)

paper · pdf · doi:10.48550/arxiv.1511.08621

openalex publication_date 2015/11/27 · openalex created_date 2016/06/24 · openalex updated_date 2026/07/28

Abstract

It was proposed earlier that Pfcrmp (Plasmodium falciparum chloroquine resistance marker protein) may be the chloroquine's target protein in nucleus. In this communication, further evidence is presented to support the view that Pfcrmp may play a key role in chloroquine antimalarial actions as well as resistance development.

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