Cystatin-C Versus Creatinine and Kidney Function in Heart Failure With Preserved Ejection Fraction: A SOGALDI-PEF Analysis

2026/06/26 by João Pedro Ferreira, Joana Mascarenhas, Pedro Marques +10
Medicine · #Chronic Kidney Disease and Diabetes #Cardiovascular Function and Risk Factors #Heart Failure Treatment and Management

paper · pdf · doi:10.1016/j.amjcard.2026.06.026

Abstract

Estimation of glomerular filtration rate (eGFR) is critical in heart failure with preserved ejection fraction (HFpEF) for informing drug dosing, treatment selection, safety monitoring, specialist referral decisions, and prognostic evaluation. The CKD-EPI (Chronic-Kidney-Disease-Epidemiology-Collaboration) creatinine equation (eGFR-Cr) is widely used in clinical practice and generally performs better than older equations such as the MDRD (Modification-of-Diet-in-Renal-Disease) and the Crockoft-Gault formula.

Citations

• A New Equation to Estimate Glomerular Filtration Rate

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