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Speckle-based X-ray microtomography via preconditioned Wirtinger flow

2025/03/26 by KyeoReh Lee, Hervé Hugonnet, Lee, KyeoReh +5
Medicine · Physics and Astronomy · #Advanced MRI Techniques and Applications #Advanced X-ray Imaging Techniques #FOS: Physical sciences #Medical Imaging Techniques and Applications #Optics (physics.optics)

paper · pdf · doi:10.48550/arxiv.2503.20146

openalex publication_date 2025/03/26 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/02

Abstract

Quantitative phase imaging has been extensively studied in X-ray microtomography to improve the sensitivity and specificity of measurements, especially for low atomic number materials. However, obtaining quantitative phase images typically requires additional measurements or assumptions, which significantly limits the practical applicability. Here, we present preconditioned Wirtinger flow (PWF): an assumption-free, single-shot quantitative X-ray phase imaging method. Accurate phase retrieval is demonstrated using a specialized gradient-based algorithm with an accurate physical model. Partial coherence of the source is taken into account, extending the potential applications to bench-top sources. Improved accuracy and spatial resolution over conventional speckle tracking methods are experimentally demonstrated. The various samples are explored to demonstrate the robustness and versatility of PWF.

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