2023/07/18 by Frank A. Greco, Greco, Frank A.
Biochemistry, Genetics and Molecular Biology · Engineering · Medicine · #FOS: Physical sciences #Medical Physics (physics.med-ph) #Non-Invasive Vital Sign Monitoring #Optical Imaging and Spectroscopy Techniques #Spectroscopy Techniques in Biomedical and Chemical Research
paper · pdf · doi:10.48550/arxiv.2307.09612
openalex publication_date 2023/07/18 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28
Scattering of light by biological tissue has hindered applications of spectroscopy to medical diagnosis. We describe here a combination of feature selection techniques and several discriminant statistics that may mitigate this problem. In the particular case of spectroscopy, a useful feature should have linewidth, which in practice means that the discriminant statistic should have significant values on several contiguous pixels of the detector. We also suggest a definition for optical taxonomic signal as a measure of how efficacious a particular combination may be and how much other variables such as source-detector separation and fiber width may affect discrimination.